Breast cancer: A comprehensive review and it’s side effect
1 Student of B. Pharmacy IV Year, Dr. Rajendra Gode College of Pharmacy, Amravati, Maharashtra, India.
2 Department of Pharmacology, Dr. Rajendra Gode College of Pharmacy, Amravati, Maharashtra, India.
3 Department of Pharmaceutical Chemistry, Dr. Rajendra Gode College of Pharmacy, Amravati, Maharashtra, India.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(02), 499–513.
Article DOI: 10.30574/wjbphs.2024.20.2.0900
Publication history:
Received on 04 October 2024; revised on 13 November 2024; accepted on 16 November 2024
Abstract:
People worldwide are impacted by breast cancer, which is a complex, multidimensional illness. The importance of understanding the intricate relationships between hormones and breast tissue is highlighted by the discovery that hormonal imbalance has been connected to the development of breast cancer. The many forms and phases of breast cancer have been clarified by the review. This comprehensive investigation looks at the involvement of key hormones, including progesterone and estrogen, and their receptors in tumor growth in an effort to clarify the significance of hormonal imbalance in breast cancer.
The review looks at the effects of hormonal imbalance on breast tissue, with a focus on how hormone receptor status affects treatment choices. The importance of hormone testing in making decisions about diagnosis and therapy, as well as the consequences of hormonal imbalance evaluation in the risk assessment of breast cancer are also covered. An important but little-known side effect of cancer is oral mucositis, which is also covered in the study. The expression "oral mucositis" describes erythematous and ulcerative lesions of the oral mucosa that occur in cancer patients' oral cavities as a result of chemotherapy or radiation therapy.
One study concluded that GI or oral mucositis developed in 303 out of 599 patients (51%) undergoing chemotherapy for solid tumors or lymphoma. This study illustrates the way a thorough knowledge of hormonal imbalance is necessary to improve breast cancer detection, treatment, and prevention strategies. The pathogenesis, clinical treatment, and risk factors of oral mucositis are also examined in this article, which will ultimately benefit those who are afflicted.
Keywords:
Breast cancer; Hormonal imbalance; Progesterone; Estrogen; Oral mucositis
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0