The future of medicine: Strategic insights into drug repurposing
Sree Abirami College of Pharmacy – 641021, Affiliated to The Tamil Nadu Dr. M. G. R. Medical University, Chennai, India.
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(02), 234–252.
Article DOI: 10.30574/wjbphs.2024.20.2.0845
Publication history:
Received on 19 September 2024; revised on 28 October 2024; accepted on 30 October 2024
Abstract:
The future of medicine is increasingly being shaped by innovative strategies that maximize the efficacy of existing therapeutics, one of the most promising being drug repurposing. Drug repurposing involves the identification of novel therapeutic applications for approved or investigational drugs, thereby circumventing the lengthy and costly processes associated with traditional drug development. This approach not only accelerates the delivery of treatments to patients but also optimizes existing resources, making it a compelling strategy in the face of rising healthcare costs and the urgent need for novel therapies.
Recent advancements in genomics, bioinformatics, and high-throughput screening have revolutionized our ability to identify potential candidates for repurposing. These technologies facilitate the exploration of drug-target interactions across various diseases, enabling researchers to uncover unexpected therapeutic potentials. For instance, well-known medications originally developed for one condition have been found effective in treating others, such as the use of thalidomide for multiple myeloma and the repurposing of antifungal agents for cancer therapy.
Keywords:
Future of medicine; Drug Repurposing; Cimetidine; Aspirin; Mefipristone; Amantadine; Zonisamide; Mebendazole
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