Impact of hypertension and diabetes on epidemiology of coronary artery disease

Ritika Deol 1, * and Vishal Saina 2

1 Clinical research intern Max super specialty, Dehradun. India.
2 Clinical research Coordinator Max super specialty, Ghaziabad., India.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(02), 564–578.
Article DOI: 10.30574/wjbphs.2024.20.2.0884
Publication history: 
Received on 02 October 2024; revised on 15 November 2024; accepted on 18 November 2024
 
Abstract: 
This study investigates the epidemiological impact of hypertension and diabetes on coronary artery disease (CAD) in a sample of 391 patients from Jodhpur, India. Focusing on the prevalence, duration, and combined effects of these conditions, we assessed their relationships with overall quality of life, treatment satisfaction, and confidence in disease management. The correlation analysis indicated no statistically significant relationships between the duration of hypertension, diabetes, or CAD and quality of life or treatment satisfaction, suggesting these conditions might not independently drive quality-of-life changes within this cohort. Multiple regression analysis highlighted that only age had a significant effect on quality of life (p = 0.025), with older patients reporting slightly higher quality-of-life scores. This model, however, accounted for only 1.9% of the variance in quality of life, underscoring the need for further exploration of other contributing factors. Ordinal logistic regression revealed no significant predictors of confidence in managing conditions, suggesting that unexamined psychosocial or clinical factors may influence patients' self-assessment of disease management capabilities. These findings underscore the multifaceted epidemiological burden of managing comorbid hypertension, diabetes, and CAD, emphasizing the need for integrative public health strategies that address both medical and quality-of-life impacts to enhance patient outcomes in CAD populations.
 
Keywords: 
Epidemiology of Coronary Artery Disease; Hypertension and Diabetes Impact; Quality of Life in CAD Patients; Disease Management Confidence; Chronic Disease Comorbidity
 
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