Assessment of anti-arthritic efficacy of the ethanolic extract of the entire Morinda citrifolia Plant

Avnish Kumar *, Swati Tiwari, Ramdarshan Parashar, Ajay Thakur and Yogesh Sharma

Department of Pharmacology, Vedic Institute of Pharmaceutical Education and Research, Babupura, Dist. Sagar Madhya Pradesh, India.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2024, 20(03), 352-357.
Article DOI: 10.30574/wjbphs.2024.20.3.1024
Publication history: 
Received on 05 November 2024; revised on 12 December 2024; accepted on 14 December 2024
 
Abstract: 
The study investigates the anti-arthritic and anti-inflammatory properties of an ethanol extract of the entire Morinda citrifolia plant in a rat model of arthritis caused by Complete Freud's Adjuvant (CFA). The extract's effectiveness was assessed by assessing key indicators of inflammation and arthritis. The results showed a substantial reduction in inflammation and arthritis-related symptoms in the treatment group, indicating that the extract had potent anti-inflammatory capabilities. The findings point out the therapeutic potential of Morinda citrifolia, a natural arthritis treatment, which may be attributable to active phytochemicals such as flavonoids and alkaloids. More research is needed to explain the underlying processes and investigate their potential application in treating human arthritis.
 
Keywords: 
Morinda citrifolia; Anti-arthritic activity; Anti-inflammatory effects; Complete Freund’s Adjuvant (CFA); Ethanol extract; Phytochemicals; Flavonoids and alkaloids; Rheumatoid arthritis model
 
Full text article in PDF: